Heart disease is a serious condition, and treatment options are limited. Fortunately, heart cell testing offers a potential cure. This process involves modifying heart cells in a culture dish, or in a human heart, to see what happens. Using these methods, doctors can test drugs and strategies that are specific to the individual heart.
Congenital heart disease
For Heart Disease Cure there are various surgical techniques available to treat congenital heart defects. These surgeries use a catheter, similar to the one used during diagnosis, to pass instruments into the heart and correct any heart defects. This type of surgery is considered minimally invasive because it does not require open heart surgery. Although it has limitations, it is a viable option for many congenital heart disease patients.
Aortic valve stenosis, or narrowing of the aortic valve, is one of the most common heart defects. This is because it limits the size of the opening of the valve, and accounts for five to eight percent of congenital heart defects. Other defects include atrial septal defect, a hole in the wall separating the right atrium from the left atrium, and coarctation of the aorta, a narrowing of the aorta’s interior space.
Coronary heart disease
There is no proven cure for coronary heart disease, but there are ways to reduce the risk and improve symptoms. For example, medicines are available to lower blood pressure and lower cholesterol. These include angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers. In addition, aspirin is a good medication for treating chest pain, and beta-blockers help the heart pump blood more efficiently.
Coronary heart disease is a condition in which the blood supply to the heart muscle is impaired. This condition is commonly caused by a buildup of plaques, fatty substances that form inside the walls of the coronary arteries. These plaques block the blood flow to the heart muscle and cause chest pain. The condition can also lead to heart failure and arrhythmias.
Cardiac bypass surgery
Cardiac bypass surgery is an option for people who are having trouble controlling their heart rate. The procedure lasts about three to six hours. Compared to other heart surgeries, it is relatively safe and the patient can return to normal activities after a few weeks. Hundreds of thousands of heart bypass surgeries are performed every year. While the surgery does carry a risk of mortality, the procedure has a high success rate.
The surgery involves making a large incision in the chest and temporarily stopping the heart. This allows the surgeon to put tubes into the heart. These tubes will be attached to the blocked artery. The bypass machine will pump blood through the body while the heart is being temporarily stopped.
Inherited heart muscle diseases
Scientists in the UK are working on a new gene-editing therapy to prevent inherited heart muscle diseases. The team at the John Radcliffe laboratory in Oxford believes that the treatment can prevent conditions like cardiomyopathy, which causes progressive heart failure and death. With the help of a PS30m grant from the British Heart Foundation, they are developing a new jab to treat patients with a genetic form of cardiomyopathy. This treatment will also help those with cardiomyopathy avoid passing their condition on to their children.
Hypertrophic cardiomyopathy is an inherited heart condition in which the heart muscle is thickened. It usually affects young children and is passed down through a family. While the disease is rare, it can lead to sudden cardiac death, particularly among young athletes.
Ajmaleen 54
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iPSC technology
A recent study found that researchers are successfully using iPSC technology to model cardiovascular disorders with a hereditary component. In order for the iPSCs to be considered useful models, they must display key phenotypic characteristics of the disease in question. This task is further complicated by the heterogeneity of the disease, genetics, and environmental factors.
Another promising application of iPSC technology in cardiovascular medicine is cell-based therapies for biological pacing. While permanent pacemakers are a viable option for treating bradyarrhythmias, they also require extensive surgery and have ongoing risks of infection. Additionally, patients may need to change lead and generators several times over their lifetime.
Transmyocardial revascularization
Transmycardial revascularization was found to be effective in relieving both acute and chronic angina. The procedure was also associated with improved quality of life and decreased use of antianginal medications. But its use should be cautiously considered. While this procedure is not a cure for heart disease, it is a viable option for patients with heart failure.
